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	Provedor de dados BJMBR (2) Autor Izquierdo,I. (2) Medina,J.H. (2) Ardenghi,P. (1) Bernabeu,R. (1) Bevilaqua,L. (1) Bianchin,M. (1) Bromberg,E. (1) Cammarota,M. (1) Quevedo,J. (1) Schaeffer,E. (1) Schmitz,P.K. (1) Schröder,N. (1) Walz,R. (1) Mais... Palavra-chave Memory formation (2) 5HT1A receptors (1) Amygdala (1) CAMP/PKA/CREB pathway (1) CAMP/PKA/CREB-P pathway (1) Dopamine D (1) Glutamate AMPA receptors (1) Hippocampus (1) Memory modulation (1) Rat hippocampus (1) Receptors (1) SS-adrenoceptors (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 1997 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Agents that affect cAMP levels or protein kinase A activity modulate memory consolidation when injected into rat hippocampus but not amygdala BJMBR Bevilaqua,L.; Ardenghi,P.; Schröder,N.; Bromberg,E.; Quevedo,J.; Schmitz,P.K.; Bianchin,M.; Walz,R.; Schaeffer,E.; Medina,J.H.; Izquierdo,I.. Male Wistar rats were trained in one-trial step-down inhibitory avoidance using a 0.4-mA footshock. At various times after training (0, 1.5, 3, 6 and 9 h for the animals implanted into the CA1 region of the hippocampus; 0 and 3 h for those implanted into the amygdala), these animals received microinfusions of SKF38393 (7.5 µg/side), SCH23390 (0.5 µg/side), norepinephrine (0.3 µg/side), timolol (0.3 µg/side), 8-OH-DPAT (2.5 µg/side), NAN-190 (2.5 µg/side), forskolin (0.5 µg/side), KT5720 (0.5 µg/side) or 8-Br-cAMP (1.25 µg/side). Rats were tested for retention 24 h after training. When given into the hippocampus 0 h post-training, norepinephrine enhanced memory whereas KT5720 was amnestic. When given 1.5 h after training, all treatments were ineffective.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Memory formation; Memory modulation; Hippocampus; Amygdala; CAMP/PKA/CREB-P pathway; Dopamine D; Receptors; SS-adrenoceptors; 5HT1A receptors. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800009 Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats BJMBR Bernabeu,R.; Cammarota,M.; Izquierdo,I.; Medina,J.H.. Training in step-down inhibitory avoidance (0.3-mA footshock) is followed by biochemical changes in rat hippocampus that strongly suggest an involvement of quantitative changes in glutamate AMPA receptors, followed by changes in the dopamine D1 receptor/cAMP/protein kinase A (PKA)/CREB-P signalling pathway in memory consolidation. AMPA binding to its receptor and levels of the AMPA receptor-specific subunit GluR1 increase in the hippocampus within the first 3 h after training (20-70%). Binding of the specific D1 receptor ligand, SCH23390, and cAMP levels increase within 3 or 6 h after training (30-100%). PKA activity and CREB-P levels show two peaks: a 35-40% increase 0 h after training, and a second increase 3-6 h later (35-60%). The results correlate... Tipo: Info:eu-repo/semantics/article Palavras-chave: Glutamate AMPA receptors; CAMP/PKA/CREB pathway; Memory formation; Rat hippocampus. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800008 Registros recuperados: 2 Primeira ... 1 ... Última

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